ANTI-CARIES FIELD STUDIES
Field trials in Japanese primary schools in the 1980s attested to the anti-caries effect of SANGI's nano<mHAP> toothpaste. In a 1-year study by researchers from Tokyo Medical and Dental University (510 children)1 and a 3-year study by researchers from former Gifu University (181 children),2 boys and girls brushed their teeth daily at lunchtime under teacher supervision with either nano<mHAP> toothpaste or an identical paste not containing nano<mHAP>. Teeth free of caries at the start of the trials and all new teeth that erupted during the trials were monitored at the end of each year for development of new caries (Decayed/Missing/Filled Teeth (DMFT) rate). Results showed that nano<mHAP> toothpaste significantly lowered the rate of new caries in both previously and newly erupted teeth, and in the 3-year study, the reduction was as high as 36-56%.